
The Effects
The physiological importance of nitric oxide was established by Nobel-prize winning research.
The physiological importance of nitric oxide was established in the 1990s and has since been confirmed by scientific studies and clinical experience.
In an open label published study, a single dose of Vascanox HP increased salivary nitric oxide levels for up to 24 hours.*†
Optimal nitric oxide levels have been shown to:
- Support a healthy cardiovascular system*
- Support and maintain blood pressure in the normal range*
- Support healthy circulation*
Vascanox HP is powered by Calroy’s proprietary blend, Noxa24®, to support the natural production, storage, and release of nitric oxide.* The formula targets nitric oxide metabolism, using multiple pathways.
The Science
Nitric oxide is a messenger molecule that is produced in the body through both nitric oxide synthase (NOS) pathway and nitrate-nitrite-nitric oxide pathway. Vascanox HP supports the entire biotransformation cycle for nitric oxide, including both pathways.*
Nitric Oxide Synthase Pathway
Nitric oxide synthases are a group of 3 enzymes catalyzing production of nitric oxide in the body. Endothelial NOS (eNOS) is primarily responsible for the generation of nitric oxide in the vascular endothelium. The mechanical force of blood flow triggers a response in the endothelial glycocalyx, which in turn signals the endothelium to generate nitric oxide.
Nitrate -> Nitrite -> Nitric Oxide Pathway
This pathway starts when inorganic nitrate, such as dietary nitrate in green leafy vegetables is ingested and absorbed into the circulation. Circulating nitrate is transported into the saliva gland and concentrated in the saliva. If secreted in the mouth, nitrate in the saliva is reduced to nitrite by nitrate reducing bacteria. Once swallowed, part of the nitrite is chemically reduced to nitric oxide in the stomach and the rest can be reduced to nitric oxide by several different enzymes after being absorbed.
The Research
We are committed to products that change lives.
Calroy is committed to the creation of science-based dietary supplements that support foundational health. We conduct clinical and scientific research to study the effects of our products.
Thoughtfully Sourced, Quality Controlled, Vegan
Vascanox HP contains a carefully curated selection of synergistic compounds derived from fruits and vegetables. In addition to potassium nitrate, a precursor for nitric oxide, a blend with polyphenols and antioxidant activities supports the entire biotransformation process for nitric oxide.
This dietary supplement is assembled using a Total Quality System, which includes strict compliance with cGMP’s current good manufacturing practices as defined by the United States Food and Drug Administration.
Batch and test records are maintained throughout the manufacturing process to ensure the guaranteed quality of the final product.
Products Without Parallel
Calroy supplement formulas are designed to protect health at its foundations. Supporting circulation, heart health, mobility, and oral health with system-focused outcomes you can feel.*
Find out why the experts trust Calroy supplements
Frequently Asked Questions
What is the difference between Arterosil HP®, Vascanox HP®, and Cartigenix HP®?
What is the difference between Arterosil HP®, Vascanox HP®, and Cartigenix HP®?
Arterosil HP® is designed to support vascular health and the endothelial glycocalyx, Vascanox HP® helps promote healthy nitric oxide production for circulation, and Cartigenix HP® supports cartilage health, joint flexibility, and mobility. They complement different aspects of overall wellness.
Can I take all three products together?
Can I take all three products together?
Yes. These formulas are designed to support different systems of the body and may be used together as part of a comprehensive wellness routine. If you are under medical supervision or taking prescription medications, consult your healthcare provider before use.
How long does it take to notice results?
How long does it take to notice results?
Results vary depending on individual health status, lifestyle, and consistency of use. Many users find that taking the products daily as directed provides the best opportunity to experience their intended benefits over time.
Are these supplements suitable for vegetarians or vegans?
Are these supplements suitable for vegetarians or vegans?
Yes. Arterosil HP®, Vascanox HP®, and Cartigenix HP® are vegan-friendly. They are also free from gluten, dairy, and soy, and are made with non-GMO ingredients.
Are these products manufactured in the USA?
Are these products manufactured in the USA?
Yes. Calroy manufactures its products in the United States using high-quality ingredients sourced from the US and around the world while following strict quality control standards.